Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | GGT1 | P19440 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843364 | 0.99 | TLR2 (0.50) | TLR2FOLH1SIGMAR1GGT1ALDH1A1 | |
| Lithium Ion SCHEMBL8843366 | 0.88 | TLR2 (0.46) | TLR2FOLH1SIGMAR1ALDH1A1UTS2R | |
| Hydrochloric Acid SCHEMBL8843391 | 0.86 | TLR2 (0.47) | TLR2SIGMAR1ALDH1A1UTS2R | |
| SCHEMBL30426128 | 0.81 | TLR2 (0.69) | TLR2FOLH1 | |
| Hydrochloric Acid SCHEMBL3229765 | 0.81 | TLR2 (0.65) | TLR2FOLH1 | |
| SCHEMBL25380272 | 0.81 | TLR2 (0.61) | TLR2FOLH1GGT1 | |
| SCHEMBL8609633 | 0.80 | TLR2 (0.57) | TLR2FOLH1SIGMAR1GGT1 | |
| SCHEMBL6714094 | 0.80 | TLR2 (0.57) | TLR2FOLH1SIGMAR1GGT1 | |
| Hydrochloric Acid SCHEMBL8843479 | 0.80 | TLR2 (0.55) | TLR2FOLH1GGT1ALDH1A1 | |
| SCHEMBL1976380 | 0.80 | TLR2 (0.67) | TLR2FOLH1GGT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672615-A | MATRIX-DEGRADING METALLOPROTEINASE INHIBITORS | NOVARTIS CORPORATION (US) | 1997-09-30 | — | — | US | disclosed |