Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2208985 | 0.77 | HTT (0.56) | HTTKMT2ASLC22A6SLC22A8MEN1 | |
| SCHEMBL6835992 | 0.73 | MEN1 (0.68) | HTTKMT2ASLC22A6SLC22A8MEN1 | |
| Apocynin SCHEMBL27893253 | 0.72 | HTT (0.65) | HTTKMT2ASLC22A6SLC22A8MEN1 | |
| SCHEMBL30921173 | 0.71 | MEN1 (0.82) | HTTKMT2ASLC22A6SLC22A8MEN1 | |
| Vanillic Acid SCHEMBL11238609 | 0.71 | HTT (0.93) | HTTKMT2ASLC22A6SLC22A8MEN1 | |
| SCHEMBL760262 | 0.71 | MEN1 (0.82) | HTTKMT2ASLC22A6SLC22A8MEN1 | |
| Vanillic Acid SCHEMBL26179 | 0.70 | HTT (1.00) | HTTKMT2ASLC22A6SLC22A8MEN1 | |
| Vanillic Acid SCHEMBL29378740 | 0.70 | HTT (1.00) | HTTKMT2ASLC22A6SLC22A8MEN1 | |
| Vanillic Acid SCHEMBL9711598 | 0.70 | HTT (1.00) | HTTKMT2ASLC22A6SLC22A8MEN1 | |
| Apocynin SCHEMBL28537029 | 0.70 | HTT (0.71) | HTTKMT2ASLC22A6SLC22A8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627173-A | Phosphonoacetic acid derivatives and their use for treating degenerative joint disorders | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-06 | — | — | US | disclosed |