SCHEMBL8844548

SCHEMBL8844548

CC(Nc1ccccc1)N[C@H]1CCCN[C@H]1c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 15/20 0.50
CYP2D6 P10635 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14414161 0.81 TACR1 (0.52) TACR1CYP2D6
SCHEMBL6669176 0.76 TACR1 (0.56) TACR1CYP2D6
SCHEMBL6669172 0.76 TACR1 (0.56) TACR1CYP2D6
SCHEMBL6669169 0.76 TACR1 (0.56) TACR1CYP2D6
SCHEMBL31401605 0.75 TACR1 (0.45) TACR1CYP2D6
SCHEMBL6670088 0.73 TACR1 (0.62) TACR1CYP2D6
SCHEMBL22570227 0.73 TACR1 (0.52) TACR1CYP2D6
SCHEMBL22570228 0.73 TACR1 (0.52) TACR1CYP2D6
SCHEMBL6670082 0.73 TACR1 (0.62) TACR1CYP2D6
SCHEMBL22570225 0.73 TACR1 (0.52) TACR1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5703065-A Heteroarylamino and heteroarylsulfonamido substituted 3-benyzlaminomethyl piperidines and related compounds PFIZER INC. (US) 1997-12-30 US disclosed