Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | POLA1 | P09884 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27972012 | 1.00 | TSHR (0.50) | TSHRCA12CA14KMT2AMEN1 | |
| SCHEMBL11811797 | 0.91 | TSHR (0.60) | TSHRCA12CA14KMT2AMEN1 | |
| SCHEMBL8844790 | 0.88 | TSHR (0.48) | TSHRCA12CA14KMT2AMEN1 | |
| SCHEMBL27972017 | 0.88 | TSHR (0.48) | TSHRCA12CA14KMT2AMEN1 | |
| SCHEMBL27918852 | 0.88 | TSHR (0.54) | TSHRCA12CA14KMT2AMEN1 | |
| SCHEMBL2992989 | 0.84 | TSHR (0.52) | TSHRCA12CA14KMT2AMEN1 | |
| SCHEMBL8844691 | 0.84 | CA12 (0.47) | TSHRCA12CA14CA2CA7 | |
| SCHEMBL8844678 | 0.84 | CA12 (0.47) | TSHRCA12CA14CA2CA7 | |
| SCHEMBL1037157 | 0.81 | TSHR (0.54) | TSHRCA12CA14KMT2AMEN1 | |
| SCHEMBL27972193 | 0.81 | CYP1A2 (0.45) | TSHRKMT2ALMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679849-A | Method of producing a bis(2-carboxyethyl)alkyl phosphine oxide and a derivative thereof | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1997-10-21 | — | — | US | disclosed |