Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845242 | 1.00 | TSHR (0.40) | TSHRALDH1A1CES1CES2FAAH | |
| SCHEMBL8845045 | 0.88 | TSHR (0.33) | TSHRALDH1A1 | |
| SCHEMBL8845043 | 0.88 | TSHR (0.33) | TSHRALDH1A1 | |
| SCHEMBL8844869 | 0.82 | TSHR (0.35) | TSHRALDH1A1 | |
| SCHEMBL346418 | 0.79 | CES1 (0.45) | TSHRALDH1A1CES1CES2TP53 | |
| SCHEMBL22546302 | 0.77 | TSHR (0.37) | TSHRALDH1A1CES1CES2FAAH | |
| SCHEMBL3821402 | 0.75 | TSHR (0.43) | TSHRALDH1A1CES1CES2FAAH | |
| SCHEMBL595267 | 0.75 | TSHR (0.43) | TSHRALDH1A1CES1CES2FAAH | |
| SCHEMBL8639717 | 0.74 | TSHR (0.42) | TSHRALDH1A1CES1CES2FAAH | |
| SCHEMBL9445646 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670580-A | POLYMERS FOR ANTISTATIC AGENTS, ADHESIVES AND FIREPROOFING | IDEMITSU KOSAN CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| EP-0486293-B1 | Thermoplastic resin compositions having improved strength and method for producing them | MITSUBISHI CHEM CORP (JP) | 1996-04-10 | — | — | EP | disclosed |
| EP-0686649-A1 | PROPYLENE BLOCK COPOLYMER, PROCESS FOR PRODUCING THE SAME, AND MODIFIED COPOLYMER PRODUCED THEREFROM | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1995-12-13 | — | — | EP | disclosed |
| US-5229463-A | Blending, crosslinking propylene copolymerized with conjugated and non-connugated dienes, EPDM rubber and crystalline propylene polymer | MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) | 1993-07-20 | — | — | US | disclosed |
| EP-0486293-A2 | Thermoplastic resin compositions having improved strength and method for producing them | MITSUBISHI CHEMICAL CORPORATION (JP) | 1992-05-20 | — | — | EP | disclosed |