Phenanthroline

Phenanthroline

SCHEMBL8845760

c1cnc2c(c1)ccc1cccnc12.c1cnc2c(c1)ccc1cccnc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 5/20 1.00
CCR8 P51685 5/20 1.00
LMNA P02545 4/20 1.00
CCR5 P51681 3/20 1.00
KDM4E B2RXH2 3/20 1.00
MMP2 P08253 2/20 1.00
TSHR P16473 2/20 1.00
MAPT P10636 2/20 1.00
HTT P42858 2/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
TDP1 Q9NUW8 2/20 1.00
GMNN O75496 1/20 1.00
TP53 P04637 1/20 1.00
HSP90AA1 P07900 1/20 1.00
CYP3A4 P08684 1/20 1.00
CYP2D6 P10635 1/20 1.00
MMP9 P14780 1/20 1.00
ALOX15 P16050 1/20 1.00
NFKB1 P19838 1/20 1.00
MMP8 P22894 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenanthroline SCHEMBL29354015 1.00 CCR1 (1.00) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL8312 1.00 CCR1 (1.00) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL29367277 1.00 CCR1 (1.00) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL21060516 0.97 CCR1 (0.94) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL22462277 0.97 CCR1 (0.94) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL22982126 0.97 CCR1 (0.94) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL21300488 0.97 CCR1 (0.94) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL21044608 0.97 CCR1 (0.94) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL3790396 0.97 CCR1 (0.94) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL345410 0.97 CCR1 (0.94) CCR1CCR8LMNACCR5KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621166-B Preparation method of 2, 5-furandicarboxylic acid 中国科学院大连化学物理研究所 2024-06-18 CN disclosed
CN-117943084-A Transition metal catalyst, preparation method and method for preparing organic acid by oxidation and pyrolysis of secondary alcohol 中国科学院大连化学物理研究所 2024-04-30 CN disclosed
CN-112368075-B Polyoxometalate compound, process for producing the same, sintered body of polyoxometalate compound, and reaction catalyst 国立大学法人静冈大学 2024-03-08 CN disclosed
WO-2020009166-A1 POLYOXOMETALATE COMPOUND AND METHOD FOR PRODUCING SAME, SINTERED BODY OF POLYOXOMETALATE COMPOUND, AND REACTION CATALYST 国立大学法人静岡大学 2020-01-09 WO disclosed
CN-106782417-B Display panel, display system, display device and its driving method 京东方科技集团股份有限公司 2019-04-16 CN disclosed
CN-106782417-A Display panel, display system, display device and its driving method 京东方科技集团股份有限公司 2017-05-31 CN disclosed
CN-104628503-B A kind of method of ethylene oligomerization 中国石油化工股份有限公司 2016-08-17 CN disclosed
CN-104628503-A Ethylene oligomerization method CHINA PETROLEUM & CHEMICAL 2015-05-20 CN disclosed
CN-102964388-B Preparation method of benzoyl-substituted 1,10-phenanthroline complex and catalytic application in ethylene oligomerization CHINA PETROLEUM & CHEMICAL 2015-03-11 CN disclosed
CN-102958899-A Process for the semi-continuous transvinylation of carboxylic acids with vinyl acetate CELANESE INT CORP 2013-03-06 CN disclosed
US-5637311-A ANTIVIRAL AGENTS AND/OR ANTIINFLAMMATORY AGENTS PROCYTE CORPORATION (US) 1997-06-10 US disclosed