Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | CES1 | P23141 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11801841 | 0.98 | TDP1 (0.67) | TDP1L3MBTL1MAPTLMNAMEN1 | |
| SCHEMBL2307268 | 0.93 | TDP1 (0.60) | TDP1L3MBTL1MAPTLMNAMEN1 | |
| SCHEMBL7760638 | 0.91 | CES1 (0.60) | TDP1L3MBTL1MAPTLMNAMEN1 | |
| SCHEMBL599568 | 0.91 | CES1 (0.60) | TDP1L3MBTL1MAPTLMNAMEN1 | |
| SCHEMBL599772 | 0.91 | CES1 (0.60) | TDP1L3MBTL1MAPTLMNAMEN1 | |
| SCHEMBL10870326 | 0.91 | TDP1 (0.58) | TDP1L3MBTL1MAPTLMNAMEN1 | |
| SCHEMBL875304 | 0.91 | CES1 (0.60) | TDP1L3MBTL1MAPTLMNAMEN1 | |
| SCHEMBL6552354 | 0.91 | CES1 (0.60) | TDP1L3MBTL1MAPTLMNAMEN1 | |
| SCHEMBL98957 | 0.91 | CES1 (0.60) | TDP1L3MBTL1MAPTLMNAMEN1 | |
| SCHEMBL98359 | 0.91 | CES1 (0.60) | TDP1L3MBTL1MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508857-B1 | Halogenated polymeric compositions stabilized by means of a mineral additive | RHONE POULENC CHIMIE (FR) | 1997-06-25 | — | — | EP | claimed |
| EP-0490780-B1 | Stabilized compositions of a chlorinated polymer | RHONE POULENC CHIMIE (FR) | 1995-06-07 | — | — | EP | claimed |
| US-5278218-A | Heat resistance | RHONE-POULENC CHIMIE (FR) | 1994-01-11 | — | — | US | claimed |
| US-5234981-A | HALOGENATED POLYMER COMPOSITIONS STABILIZED WITH THE AID OF AN INORGANIC ADDITIVE | RHONE-POULENC CHIMIE (FR) | 1993-08-10 | — | — | US | claimed |
| EP-0046161-A2 | Stabilized Polyvinylhalide resin | PHOENIX CHEMICAL CORPORATION (US) | 1982-02-24 | — | — | EP | claimed |
| US-5278218-A | Heat resistance | RHONE-POULENC CHIMIE (FR) | 1994-01-11 | — | — | US | disclosed |
| US-5234981-A | HALOGENATED POLYMER COMPOSITIONS STABILIZED WITH THE AID OF AN INORGANIC ADDITIVE | RHONE-POULENC CHIMIE (FR) | 1993-08-10 | — | — | US | disclosed |
| US-5200444-A | Polymer matrices heat and light stabilized with novel benzophenone/1,4-dihydropyridine compounds | RHONE-POULENC CHIMIE (FR) | 1993-04-06 | — | — | US | disclosed |
| US-5194470-A | Nonyellowing polymer compositions for heat stability | RHONE-POULENC CHIMIE (FR) | 1993-03-16 | — | — | US | disclosed |
| EP-0286887-B1 | POLY 1,4-DIHYDRO-2,6-DIMETHYLPYRIDINE-3,5-DICARBOXYLESTERS USEFUL AS THERMAL STABILIZERS FOR SYNTHETIC POLYMERS | LAGOR SPA (IT) | 1992-11-11 | — | — | EP | disclosed |
| US-5143959-A | Mixture of dawsonite, hydrotalcite, polysiloxane and organometallic compound; heat resistant | RHONE-POULENC CHIMIE (FR) | 1992-09-01 | — | — | US | disclosed |
| US-5124456-A | HINDERED AMINE-SUBSTITUTED DIHYDROPYRIDINES AND HEAT/LIGHT STABILIZATION OF POLYMER SUBSTRATES THEREWITH | RHONE-POULENC CHIMIE (FR) | 1992-06-23 | — | — | US | disclosed |
| US-5070128-A | ORGANOZINC AND ORGANOALKALINE EARTH COMPOUNDS, SODIUM BETA-DIK ETONATE AS STABILIZERS | RHONE-POULENC CHIMIE (FR) | 1991-12-03 | — | — | US | disclosed |
| US-5034533-A | Polyesterether copolymers as stabilizers for polymers | RHONE-POULENC CHIMIE (FR) | 1991-07-23 | — | — | US | disclosed |
| US-4908398-A | For vinyl chloride polymers | LAGOR S.P.A. (IT) | 1990-03-13 | — | — | US | disclosed |
| EP-0286887-A1 | Poly 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylesters useful as thermal stabilizers for synthetic polymers | LAGOR SPA (IT) | 1988-10-19 | — | — | EP | disclosed |
| EP-0046161-B1 | STABILIZED POLYVINYLHALIDE RESIN | PHOENIX CHEMICAL CORPORATION (US) | 1986-11-12 | — | — | EP | disclosed |
| US-4371651-A | PHOTOSTABILITY, HEAT RESISTANCE | PHOENIX CHEMICAL CORPORATION (US) | 1983-02-01 | — | — | US | disclosed |
| EP-0046161-A2 | Stabilized Polyvinylhalide resin | PHOENIX CHEMICAL CORPORATION (US) | 1982-02-24 | — | — | EP | disclosed |
| US-3994869-A | Photodegradable polyolefins containing aryl-substituted 1,3-diones | ICI UNITED STATES INC. (US) | 1976-11-30 | — | — | US | disclosed |