Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 15/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | HMGCR | P04035 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 3/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6958682 | 0.89 | AR (0.53) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL6963764 | 0.85 | ESR1 (0.50) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL9261550 | 0.85 | ESR1 (0.50) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL6958229 | 0.83 | GCGR (0.70) | GCGR | |
| SCHEMBL9270541 | 0.78 | HMGCR (0.62) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL9270549 | 0.78 | HMGCR (0.62) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL6956310 | 0.77 | HMGCR (0.60) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL9265076 | 0.76 | GCGR (0.56) | GCGRAR | |
| SCHEMBL27299931 | 0.76 | HMGCR (0.71) | ESR1HMGCRCHRM1TBXA2RPDE4A | |
| SCHEMBL6961134 | 0.76 | HMGCR (0.64) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641762-B1 | Process for preparation of 5-hydroxy-3-ketoester derivative and optically active substance thereof | UBE INDUSTRIES (JP) | 1997-05-28 | — | — | EP | disclosed |
| US-5457225-A | Process for preparation of 5-hydroxy-3-ketoester derivative and optically active substance thereof | UBE INDUSTRIES LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| EP-0641762-A1 | Process for preparation of 5-hydroxy-3-ketoester derivative and optically active substance thereof | UBE INDUSTRIES, LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |