SCHEMBL8846458

SCHEMBL8846458

O=C(O)c1cccc(C(=O)OCCCCOO)c1

nearest known ligand 0.62

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.62
LMNA P02545 1/20 0.46
HDAC6 Q9UBN7 1/20 0.44
KMT2A Q03164 1/20 0.44
CNR2 P34972 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL209607 0.93 TDP1 (0.71) TDP1LMNAHDAC6KMT2A
SCHEMBL9436550 0.91 TDP1 (0.69) TDP1LMNAHDAC6KMT2A
SCHEMBL28188778 0.91 TDP1 (0.69) TDP1LMNAHDAC6KMT2A
SCHEMBL212972 0.91 TDP1 (0.69) TDP1LMNAHDAC6KMT2A
SCHEMBL10867635 0.91 TDP1 (0.69) TDP1LMNAHDAC6KMT2A
Terephthalic Acid SCHEMBL5611007 0.88 TDP1 (0.65) TDP1LMNAHDAC6
SCHEMBL9421257 0.88 TDP1 (0.62) TDP1LMNAKMT2A
SCHEMBL11723807 0.87 TDP1 (0.62) TDP1LMNAHDAC6
SCHEMBL1475118 0.87 TDP1 (0.62) TDP1LMNAHDAC6
SCHEMBL27574211 0.86 TDP1 (0.60) TDP1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61148221-A None JP disclosed
EP-0549338-B1 Polyacetal resin composition POLYPLASTICS CO (JP) 1997-07-30 EP disclosed
JP-S61148221-A ACETAL RESIN COMPOSITION MITSUBISHI GAS CHEM CO INC 1986-07-05 JP disclosed