Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.56 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | ECE1 | P42892 | 4/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8846613 | 0.94 | ERAP2 (0.62) | ACEERAP2PPARGECE1LTA4H | |
| SCHEMBL644404 | 0.92 | ERAP2 (0.60) | ACEERAP2PPARGALOX15 | |
| SCHEMBL645413 | 0.92 | ERAP2 (0.60) | ACEERAP2PPARGALOX15 | |
| SCHEMBL642931 | 0.92 | ERAP2 (0.60) | ACEERAP2PPARGALOX15 | |
| SCHEMBL27780903 | 0.92 | ERAP2 (0.60) | ACEERAP2PPARGALOX15 | |
| SCHEMBL643229 | 0.92 | ERAP2 (0.60) | ACEERAP2PPARGALOX15 | |
| SCHEMBL30997441 | 0.91 | ACE (0.61) | ACEERAP2ECE1ALOX15 | |
| Ammonia Solution, Strong SCHEMBL645221 | 0.91 | ERAP2 (0.59) | ACEERAP2PPARGALOX15 | |
| Calcium SCHEMBL730968 | 0.91 | ERAP2 (0.59) | ACEERAP2PPARGALOX15 | |
| Magnesium SCHEMBL730627 | 0.91 | KDM4E (0.61) | ACEERAP2PPARGALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0768888-A1 | USE OF MURAMYL PEPTIDE COMPOUNDS | PEPTECH (UK) LIMITED (GB) | 1997-04-23 | — | — | EP | disclosed |
| EP-0722332-A1 | COMPOUNDS FOR MEDICINAL USE | PEPTECH (UK) LIMITED (GB) | 1996-07-24 | — | — | EP | disclosed |
| WO-1996001645-A1 | USE OF MURAMYL PEPTIDE COMPOUNDS | PEPTECH(UK) LIMITED (GB) | 1996-01-25 | — | — | WO | disclosed |
| WO-1995010293-A1 | COMPOUNDS FOR MEDICINAL USE | PEPTECH (UK) LIMITED (GB) | 1995-04-20 | — | — | WO | disclosed |