Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 17/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 14/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6669000 | 0.85 | ESR1 (0.69) | ESR1ESR2KCNH2HRH3 | |
| SCHEMBL29362450 | 0.85 | ESR1 (0.69) | ESR1ESR2KCNH2HRH3 | |
| SCHEMBL8486984 | 0.84 | ESR1 (0.68) | ESR1ESR2KCNH2HRH3 | |
| SCHEMBL7938790 | 0.82 | ESR1 (0.82) | ESR1ESR2 | |
| SCHEMBL7941540 | 0.76 | ESR1 (0.71) | ESR1ESR2KCNH2HRH3 | |
| SCHEMBL8903074 | 0.76 | ESR1 (0.76) | ESR1ESR2 | |
| SCHEMBL9247758 | 0.75 | ESR1 (0.69) | ESR1ESR2KCNH2HRH3 | |
| SCHEMBL30076531 | 0.74 | ESR1 (0.89) | ESR1ESR2 | |
| SCHEMBL5120828 | 0.73 | ESR1 (0.75) | ESR1ESR2 | |
| SCHEMBL5108258 | 0.73 | ESR1 (0.75) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811006-A1 | BENZOPYRAN-CONTAINING COMPOUNDS AND METHOD FOR THEIR USE | ENDORECHERCHE INC. (CA) | 1997-12-10 | — | — | EP | disclosed |
| WO-1996026201-A1 | BENZOPYRAN-CONTAINING COMPOUNDS AND METHOD FOR THEIR USE | ENDORECHERCHE, INC. (CA) | 1996-08-29 | — | — | WO | disclosed |