SCHEMBL8849189

SCHEMBL8849189

Cc1ccn(Cn2ccc(C)n2)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.42
RAB9A P51151 3/20 0.40
MAPT P10636 2/20 0.40
NPC1 O15118 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
NOS1 P29475 1/20 0.40
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 1/20 0.39
GFER P55789 1/20 0.38
AKR1C3 P42330 1/20 0.37
AKR1C2 P52895 1/20 0.37
AKR1C1 Q04828 1/20 0.37
DRD2 P14416 1/20 0.36
HTR2A P28223 1/20 0.36
HRH1 P35367 1/20 0.36
THRB P10828 1/20 0.36
HTT P42858 2/20 0.33
TDO2 P48775 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL255119 0.82
SCHEMBL3589576 0.80
SCHEMBL6864001 0.80
SCHEMBL293669 0.78
SCHEMBL12126092 0.77
SCHEMBL1780286 0.77
SCHEMBL12165181 0.77 GAA (0.38) GAARAB9AMAPTNPC1SMN1; SMN2
SCHEMBL10049904 0.77
SCHEMBL984869 0.77
SCHEMBL11221648 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0799168-A1 USE OF PYRAZOLE DERIVATIVES WITH HYDROPHOBIC GROUPS AS NITRIFICATION INHIBITORS BASF AKTIENGESELLSCHAFT (DE) 1997-10-08 EP claimed
WO-1996020146-A1 USE OF PYRAZOLE DERIVATIVES WITH HYDROPHOBIC GROUPS AS NITRIFICATION INHIBITORS BASF AKTIENGESELLSCHAFT (DE) 1996-07-04 WO claimed
EP-0799168-A1 USE OF PYRAZOLE DERIVATIVES WITH HYDROPHOBIC GROUPS AS NITRIFICATION INHIBITORS BASF AKTIENGESELLSCHAFT (DE) 1997-10-08 EP disclosed
WO-1996020146-A1 USE OF PYRAZOLE DERIVATIVES WITH HYDROPHOBIC GROUPS AS NITRIFICATION INHIBITORS BASF AKTIENGESELLSCHAFT (DE) 1996-07-04 WO disclosed