Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8849248 | 1.00 | TSHR (0.60) | TSHRGAAKMT2AMEN1CHRNA7 | |
| SCHEMBL9421818 | 0.88 | TSHR (0.45) | TSHRGAAKMT2AMEN1LMNA | |
| SCHEMBL9421822 | 0.88 | TSHR (0.45) | TSHRGAAKMT2AMEN1LMNA | |
| SCHEMBL11220482 | 0.87 | TSHR (0.62) | TSHRGAAKMT2AMEN1CHRNA7 | |
| SCHEMBL27690100 | 0.82 | TSHR (0.67) | TSHRGAAKMT2AMEN1CHRNA7 | |
| SCHEMBL9657743 | 0.82 | TSHR (0.71) | TSHRGAAKMT2AMEN1CHRNA7 | |
| SCHEMBL10461194 | 0.81 | TSHR (0.65) | TSHRGAAKMT2AMEN1CHRNA7 | |
| SCHEMBL10408563 | 0.80 | TSHR (0.64) | TSHRGAAKMT2AMEN1CHRNA7 | |
| SCHEMBL243559 | 0.79 | TSHR (0.70) | TSHRGAAKMT2AMEN1CHRNA7 | |
| SCHEMBL51072 | 0.79 | TSHR (0.70) | TSHRGAAKMT2AMEN1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499581-B1 | Stabilized polymer composition | CIBA GEIGY AG (CH) | 1997-07-09 | — | — | EP | disclosed |
| EP-0479725-B1 | Stabilized styrene copolymers containing elastomer particles | CIBA GEIGY AG (CH) | 1995-04-26 | — | — | EP | disclosed |
| US-5288777-A | Adding sterically hindered piperidines | CIBA-GEIGY CORPORATION (US) | 1994-02-22 | — | — | US | disclosed |
| EP-0337431-B1 | STABILIZED STYRENE COPOLYMER COMPRISING ELASTOMER PARTICLES | CIBA-GEIGY AG (CH) | 1993-06-23 | — | — | EP | disclosed |
| US-5194465-A | Photostability, graft polymers, unsaturated hindered amine modifier | CIBA-GEIGY CORPORATION (US) | 1993-03-16 | — | — | US | disclosed |
| EP-0499581-A1 | Stabilized polymer composition | CIBA-GEIGY AG (CH) | 1992-08-19 | — | — | EP | disclosed |
| US-5135986-A | Graft polymers of styrene or A-methylstyrene and a comonomer on a core of elastomer modified by a steric hindered unsaturated 2,2,6,6-tetramethylpiperidine compoune; photostability | CIBA-GEIGY CORPORATION (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0479725-A2 | Stabilized styrene copolymers containing elastomer particles | CIBA-GEIGY AG (CH) | 1992-04-08 | — | — | EP | disclosed |
| EP-0337431-A2 | Stabilized styrene copolymer comprising elastomer particles | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | disclosed |