SCHEMBL8850828

SCHEMBL8850828

C=C(C)C(=O)OCCC[Si](OCC)(OCC)OCC.C=C[Si](OCC)(OCC)OCC

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.46
THRB P10828 1/20 0.44
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6216027 0.92 TSHR (0.44) TSHRTHRBPOLBAPEX1HTT
SCHEMBL19411012 0.92 TSHR (0.44) TSHRTHRBPOLBAPEX1HTT
SCHEMBL10650071 0.91 TSHR (0.41) TSHRTHRBPOLBAPEX1HTT
SCHEMBL19410342 0.91 TSHR (0.43) TSHRTHRBPOLBAPEX1HTT
Propene SCHEMBL28175468 0.90 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL25235967 0.90 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL37108 0.90 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
Hydrogen Sulfide SCHEMBL329936 0.88 TSHR (0.54) TSHRTHRBPOLBAPEX1HTT
SCHEMBL14060478 0.88 TSHR (0.54) TSHRTHRBPOLBAPEX1HTT
Methyl Alcohol SCHEMBL28830046 0.88 TSHR (0.54) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0741759-B1 REDISPERSIBLE SILICON-MODIFIED DISPERSION POWDER COMPOSITION, METHOD OF MANUFACTURING IT AND ITS USE WACKER CHEMIE GMBH (DE) 1997-10-15 EP disclosed
EP-0741759-A1 REDISPERSIBLE SILICON-MODIFIED DISPERSION POWDER COMPOSITION, METHOD OF MANUFACTURING IT AND ITS USE WACKER CHEMIE GMBH (DE) 1996-11-13 EP disclosed
WO-1995020626-A1 REDISPERSIBLE SILICON-MODIFIED DISPERSION POWDER COMPOSITION, METHOD OF MANUFACTURING IT AND ITS USE WACKER-CHEMIE GMBH (DE) 1995-08-03 WO disclosed
US-5281636-A Protective topcoatings for automobiles with torage stability KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1994-01-25 US disclosed