Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.51 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL469641 | 1.00 | KCNH2 (0.59) | KCNH2TDP1L3MBTL1SIGMAR1HTR2A | |
| SCHEMBL19322733 | 1.00 | KCNH2 (0.59) | KCNH2TDP1L3MBTL1SIGMAR1HTR2A | |
| SCHEMBL2670017 | 1.00 | KCNH2 (0.59) | KCNH2TDP1L3MBTL1SIGMAR1HTR2A | |
| SCHEMBL22268758 | 1.00 | KCNH2 (0.59) | KCNH2TDP1L3MBTL1SIGMAR1HTR2A | |
| Ammonia Solution, Strong SCHEMBL28095936 | 0.98 | KCNH2 (0.57) | KCNH2TDP1L3MBTL1SIGMAR1HTR2A | |
| SCHEMBL18874443 | 0.96 | TDP1 (0.61) | KCNH2TDP1L3MBTL1SIGMAR1HTR2A | |
| SCHEMBL18511816 | 0.96 | TDP1 (0.61) | KCNH2TDP1L3MBTL1SIGMAR1HTR2A | |
| SCHEMBL18483888 | 0.96 | TDP1 (0.61) | KCNH2TDP1L3MBTL1SIGMAR1HTR2A | |
| SCHEMBL7905269 | 0.96 | TDP1 (0.61) | KCNH2TDP1L3MBTL1SIGMAR1HTR2A | |
| SCHEMBL27396395 | 0.96 | HRH3 (0.55) | KCNH2TDP1L3MBTL1SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102725269-B | synthetic intermediate of oxazole compound and preparation method thereof | OTSUKA PHARMA CO LTD | 2015-03-25 | — | — | CN | disclosed |
| CN-102725269-A | Synthetic intermediate of oxazole compound and preparation method thereof | OTSUKA PHARMA CO LTD | 2012-10-10 | — | — | CN | disclosed |
| CN-101675044-B | Epoxy compound and process for producing the same | OTSUKA PHARMA CO LTD | 2012-10-03 | — | — | CN | disclosed |
| CN-101675044-A | Epoxy compound and process for producing the same | OTSUKA PHARMA CO LTD | 2010-03-17 | — | — | CN | disclosed |
| CN-1326840-C | 1-substituted-4-nitroimidazole compounds and process for preparing same | OTSUKA PHARMA CO LTD (JP) | 2007-07-18 | — | — | CN | disclosed |
| CN-1692103-A | 1-substituted-4-nitroimidazole compounds and process for preparing same | OTSUKA PHARMA CO LTD (JP) | 2005-11-02 | — | — | CN | disclosed |
| CN-1131213-C | Carbostyril derivatives as antithrombotic agents | NISHI MEDICAL RES INST CO LTD (JP) | 2003-12-17 | — | — | CN | disclosed |
| US-5633289-A | Process for molding an integral skin foam and a polyurethane material for molding the same | TOYODA GOSEI CO., LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| CN-1112364-A | Piperazine derivatives and salts thereof | OTSUKA PHARMA CO LTD (JP) | 1995-11-22 | — | — | CN | disclosed |