Benzene

Benzene

SCHEMBL8854020

CCCCO[PH](=O)OCCCC.c1ccccc1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.39
CYP3A4 P08684 3/20 0.37
TSHR P16473 5/20 0.36
TDP1 Q9NUW8 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
ADRB2 P07550 1/20 0.36
ADRB1 P08588 1/20 0.36
ADRB3 P13945 1/20 0.36
ALDH1A1 P00352 3/20 0.36
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CYP1A2 P05177 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
TP53 P04637 1/20 0.33
LMNA P02545 1/20 0.33
PDE4D Q08499 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
ATM Q13315 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20236 0.92 CYP3A4 (0.42) CYP3A4TSHRTDP1L3MBTL1ADRB2
Benzene SCHEMBL8854030 0.91 TSHR (0.40) LTA4HTSHRALDH1A1CA1CA2
Benzene SCHEMBL9260420 0.91 TSHR (0.40) LTA4HTSHRALDH1A1CA1CA2
Hydrochloric Acid SCHEMBL29060497 0.90 CYP3A4 (0.40) CYP3A4TSHRTDP1L3MBTL1ADRB2
SCHEMBL10424280 0.90 CYP3A4 (0.40) CYP3A4TSHRTDP1L3MBTL1ADRB2
SCHEMBL7717490 0.90 CYP3A4 (0.40) CYP3A4TSHRTDP1L3MBTL1ADRB2
SCHEMBL28699955 0.90 CYP3A4 (0.40) CYP3A4TSHRTDP1L3MBTL1ADRB2
Butane SCHEMBL7118944 0.90 CYP3A4 (0.40) CYP3A4TSHRTDP1L3MBTL1ADRB2
Hexane SCHEMBL11874448 0.90 CYP3A4 (0.40) CYP3A4TSHRADRB2ADRB1ADRB3
SCHEMBL30218355 0.90 CYP3A4 (0.40) CYP3A4TSHRTDP1L3MBTL1ADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5620762-A MIXTURE FREE OF HALIDE SALT AND CONTAINING A POLYAMIDE, ACRYLONITRILE-BUTADIENE COPOLYMER, A PLASTICIZER, A STABILIZER, A CROSSLINKING AGENT AND A FILLER; LAP RESISTANCE TO THE FIBER-WORKING SURFACE ARMSTRONG WORLD INDUSTRIES, INC. (US) 1997-04-15 US disclosed
US-4349526-A TRI-SUBSTITUTED PHENYLUREAS AS SOLVENT IN ANTHRAQUINONE PROCESS DEGUSSA AKTIENGESELLSCHAFT (DE) 1982-09-14 US disclosed