Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CPT2 | P23786 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15321752 | 0.83 | HMGCR (0.39) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL15703179 | 0.81 | HMGCR (0.38) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL29641980 | 0.79 | HMGCR (0.37) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL621725 | 0.78 | FFAR1 (0.39) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL15321176 | 0.78 | FFAR1 (0.39) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL1176 | 0.75 | HMGCR (0.47) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL10891642 | 0.73 | FFAR1 (0.65) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| Mevalonic Acid SCHEMBL120276 | 0.71 | HMGCR (0.67) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| Mevalonic Acid SCHEMBL120275 | 0.71 | HMGCR (0.67) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| Mevalonic Acid SCHEMBL8854071 | 0.71 | HMGCR (0.67) | HMGCRCHRM1TBXA2RADRA1AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591648-A | Antibodies for mevalonic acid and methods for immunological determination of mevalonic acid by using them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0383248-B1 | Process for the production of mevalonic acid | ASAHI DENKA KOGYO KK (JP) | 1993-12-15 | — | — | EP | disclosed |
| US-5100789-A | Culture medium contains casein derived peptone and corn steep liquor | ASHAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 1992-03-31 | — | — | US | disclosed |
| EP-0383248-A1 | Process for the production of mevalonic acid | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 1990-08-22 | — | — | EP | disclosed |