SCHEMBL8854136

SCHEMBL8854136

OP(=S)(S)CCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
CYP2D6 P10635 1/20 0.46
TDP1 Q9NUW8 2/20 0.44
POLB P06746 1/20 0.44
CETP P11597 1/20 0.43
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
CASP1 P29466 1/20 0.41
HSD17B10 Q99714 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
ANPEP P15144 2/20 0.40
ERAP1 Q9NZ08 2/20 0.40
TAAR1 Q96RJ0 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
ATM Q13315 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6681829 0.79 HPGD (0.46) TSHRTDP1ALDH1A1HPGDALOX12
SCHEMBL8371905 0.75 TSHR (0.57) TSHRCYP2D6TDP1POLBCETP
SCHEMBL6030731 0.73 TSHR (0.88) TSHRCYP2D6TDP1POLBCETP
SCHEMBL1101314 0.73 TSHR (0.67) TSHRCYP2D6POLBCETPALDH1A1
SCHEMBL6310524 0.72 HPGD (0.48) TSHRTDP1ALDH1A1HPGDALOX12
SCHEMBL28543472 0.71 TSHR (0.64) TSHRCYP2D6POLBCETPALDH1A1
SCHEMBL2517900 0.71 TSHR (0.84) TSHRCYP2D6TDP1POLBCETP
SCHEMBL3862229 0.70 TSHR (0.62) TSHRCYP2D6POLBCETPANPEP
SCHEMBL20626773 0.70 TSHR (0.62) TSHRCYP2D6TDP1POLBCETP
SCHEMBL5460196 0.70 CA1 (0.42) TDP1ALDH1A1HPGDALOX15ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5650161-A Safened pesticidal resin compositions for controlling soil borne pests and process for the preparation thereof AMERICAN CYANAMID COMPANY (US) 1997-07-22 US disclosed
US-5650163-A DRY BLENDING PESTICIDAL COMPOSITION, COOLING, EXTRUDING AND CUTTING RESULTING MIXTURE INTO PELLETS AMERICAN CYANAMID COMPANY (US) 1997-07-22 US disclosed
US-5645843-A APPLYING TO SOIL, COMPOSITIONS CONTAINING POLYVINYLIC SUSPENSION, HEAT STABILIZERS, LUBRICANT, PLASTICIZER AND MINERAL ADDITIVE AMERICAN CYANAMID COMPANY (US) 1997-07-08 US disclosed
US-5645847-A VINYL RESIN BASF AKTIENGESELLSCHAFT 1997-07-08 US disclosed
US-5643590-A INSECTICIDES FOR SOILS USING A RESIN SUSPENSION, STABILIZERS, LUBRICANTS, PLASTICIZERS, MINERALS AND SILICON DIOXIDE AMERICAN CYANAMID COMPANY (US) 1997-07-01 US disclosed
EP-0268927-A2 Resin-coated, non-sorptive granular, pesticidal compositions and method for the preparation thereof AMERICAN CYANAMID COMPANY (US) 1988-06-01 EP disclosed