⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22207074 | 1.00 | — | — | |
| SCHEMBL22207072 | 0.80 | EP300 (0.47) | — | |
| SCHEMBL28071891 | 0.74 | — | — | |
| SCHEMBL23706368 | 0.73 | — | — | |
| SCHEMBL7576376 | 0.72 | — | — | |
| SCHEMBL20705369 | 0.72 | — | — | |
| SCHEMBL232643 | 0.71 | — | — | |
| SCHEMBL232642 | 0.71 | — | — | |
| SCHEMBL22551040 | 0.71 | — | — | |
| SCHEMBL3815138 | 0.70 | BACE1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282547-A4 | METHOD FOR CONTROLLING EMESIS CAUSED BY CHEMOTHERAPEUTIC AGENTS AND ANTIEMETIC AGENTS USEFUL THEREIN | — | 1990-11-28 | — | — | EP | claimed |
| EP-0282547-A1 | METHOD FOR CONTROLLING EMESIS CAUSED BY CHEMOTHERAPEUTIC AGENTS AND ANTIEMETIC AGENTS USEFUL THEREIN. | ADRIA LAB INC (US) | 1988-09-21 | — | — | EP | claimed |
| WO-1988001866-A1 | METHOD FOR CONTROLLING EMESIS CAUSED BY CHEMOTHERAPEUTIC AGENTS AND ANTIEMETIC AGENTS USEFUL THEREIN | ADRIA LABORATORIES, INC. (US) | 1988-03-24 | — | — | WO | claimed |
| US-5646303-A | Method for controlling emesis caused by chemotherapeutic agents and antiemetic agents useful therein | PHARMACIA INC. (US) | 1997-07-08 | — | — | US | disclosed |
| EP-0282547-A4 | METHOD FOR CONTROLLING EMESIS CAUSED BY CHEMOTHERAPEUTIC AGENTS AND ANTIEMETIC AGENTS USEFUL THEREIN | — | 1990-11-28 | — | — | EP | disclosed |
| EP-0282547-A1 | METHOD FOR CONTROLLING EMESIS CAUSED BY CHEMOTHERAPEUTIC AGENTS AND ANTIEMETIC AGENTS USEFUL THEREIN. | ADRIA LAB INC (US) | 1988-09-21 | — | — | EP | disclosed |
| US-4772459-A | N-(PYRROLIDINYL-OR PIPERIDINYLALKYL) ETHER-SUBSTITUTED BENZAMIDES | ERBAMONT, INC. (US) | 1988-09-20 | — | — | US | disclosed |
| WO-1988001866-A1 | METHOD FOR CONTROLLING EMESIS CAUSED BY CHEMOTHERAPEUTIC AGENTS AND ANTIEMETIC AGENTS USEFUL THEREIN | ADRIA LABORATORIES, INC. (US) | 1988-03-24 | — | — | WO | disclosed |