Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.74 |
| ▸ | Q9HBH1 | 7/20 | 0.34 | |
| ▸ | STAT6 | P42226 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13660108 | 1.00 | TUBB1 (0.74) | TUBB1PDFSTAT6 | |
| SCHEMBL58085 | 1.00 | TUBB1 (0.74) | TUBB1PDFSTAT6 | |
| SCHEMBL24360627 | 0.94 | TUBB1 (0.70) | TUBB1PDF | |
| SCHEMBL12201633 | 0.93 | TUBB1 (0.69) | TUBB1PDF | |
| SCHEMBL15434851 | 0.91 | TUBB1 (0.67) | TUBB1PDF | |
| SCHEMBL27400350 | 0.91 | TUBB1 (0.63) | TUBB1PDF | |
| SCHEMBL20822463 | 0.91 | TUBB1 (0.65) | TUBB1 | |
| SCHEMBL14567801 | 0.90 | TUBB1 (0.66) | TUBB1PDF | |
| SCHEMBL13660110 | 0.90 | TUBB1 (0.66) | TUBB1PDF | |
| SCHEMBL58040 | 0.90 | TUBB1 (0.66) | TUBB1PDF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633224-B2 | Hemiasterlin derivatives and uses thereof in the treatment of cancer | EISAI CO., LTD. (JP) | 2014-01-21 | — | — | US | disclosed |
| US-8633224-B2 | Hemiasterlin derivatives and uses thereof in the treatment of cancer | EISAI CO., LTD. (JP) | 2014-01-21 | — | — | US | disclosed |