SCHEMBL8856052

SCHEMBL8856052

C=CCNCCCC=C(C)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C19 P33261 1/20 0.42
KDM4E B2RXH2 9/20 0.41
LMNA P02545 1/20 0.41
ALDH1A1 P00352 5/20 0.40
GAA P10253 2/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
POLB P06746 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.35
HTT P42858 1/20 0.34
TSHR P16473 1/20 0.32
MAPT P10636 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16340123 0.95 KMT2A (0.44) KMT2AMEN1CYP1A2CYP3A4CYP2D6
SCHEMBL1489811 0.89 POLB (0.39) KMT2AMEN1CYP1A2CYP3A4CYP2D6
SCHEMBL18579303 0.85 KDM4E (0.35) KMT2AMEN1CYP1A2CYP3A4CYP2D6
SCHEMBL636778 0.80 CYP2C19 (0.39) KMT2AMEN1CYP1A2CYP2C19TSHR
SCHEMBL636776 0.80 CYP2C19 (0.39) KMT2AMEN1CYP1A2CYP2C19TSHR
SCHEMBL635766 0.79 PAOX (0.48) KMT2AMEN1KDM4EALDH1A1GAA
SCHEMBL635764 0.79 PAOX (0.48) KMT2AMEN1KDM4EALDH1A1GAA
SCHEMBL2497944 0.79 PAOX (0.42) KMT2AMEN1CYP1A2CYP2C19KDM4E
SCHEMBL432888 0.79 EP300 (0.44) KMT2AMEN1KDM4EALDH1A1GAA
SCHEMBL23829765 0.77 MAPT (0.43) CYP3A4CYP2D6CYP2C19LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10718960-B2 Method for producing contact lenses with wearing comfort ALCON INC. (CH) 2020-07-21 US disclosed
EP-3532276-A1 METHOD FOR PRODUCING SURFACE COATED CONTACT LENSES WITH WEARING COMFORT Novartis AG (CH) 2019-09-04 EP disclosed
EP-3344447-A1 METHOD FOR PRODUCING CONTACT LENSES WITH DURABLE LUBRICIOUS COATINGS THEREON Novartis AG (CH) 2018-07-11 EP disclosed
US-20180120590-A1 METHOD FOR PRODUCING CONTACT LENSES WITH WEARING COMFORT ALCON INC. (CH) 2018-05-03 US disclosed
US-9810812-B2 Method for producing contact lenses with durable lubricious coatings thereon NOVARTIS AG (CH) 2017-11-07 US disclosed
US-20170068019-A1 METHOD FOR PRODUCING CONTACT LENSES WITH DURABLE LUBRICIOUS COATINGS THEREON ALCON INC. (CH) 2017-03-09 US disclosed
EP-3013874-B1 ADDITIVE THAT IMPROVES ADHESION AND COATING COMPOUND CONTAINING THE SAME BYK CHEMIE GMBH (DE) 2016-12-14 EP disclosed
EP-3013874-A1 ADHESION-STRENGTHENING ADDITIVE AND COATING COMPOSITION CONTAINING SAME BYK-Chemie GmbH (DE) 2016-05-04 EP disclosed
WO-2014206962-A1 ADHESION-STRENGTHENING ADDITIVE AND COATING COMPOSITION CONTAINING SAME BYK-CHEMIE GMBH (DE) 2014-12-31 WO disclosed
US-5629066-A A COATED RESIN LAYER COVERING THE SURFACE OF FILM OR SHEET, IS MADE OF AN AMINO GROUP CONTAINING POLYMER AND/OR A POLYMER OF METHACRYLATE OF ISOCYANURIC ACID, HAVING AN EXPOSED SURFACE QUATERNIZED WITH ALKYL SULFATE OR SULFONATES TEIJIN LIMITED (JP) 1997-05-13 US disclosed
EP-0519420-B1 Resin article having anti-static property TEIJIN LTD (JP) 1995-12-20 EP disclosed
EP-0519420-A1 Resin article having anti-static property TEIJIN LIMITED (JP) 1992-12-23 EP disclosed