SCHEMBL885606

SCHEMBL885606

Nc1ccccc1N1C(=O)c2ccccc2C1=O

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SCN2A Q99250 1/20 0.57
POLB P06746 1/20 0.55
CYP3A4 P08684 1/20 0.53
NFKB1 P19838 1/20 0.53
PMP22 Q01453 1/20 0.53
HSPA1A P0DMV8 1/20 0.52
PABPC1 P11940 1/20 0.52
KDM4E B2RXH2 1/20 0.50
GAA P10253 1/20 0.50
NR1H3 Q13133 4/20 0.49
NR1H2 P55055 3/20 0.49
ADORA2A P29274 1/20 0.47
CASP1 P29466 1/20 0.47
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
DPP4 P27487 1/20 0.44
ALDH1A1 P00352 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29395615 1.00 SCN2A (0.57) SCN2APOLBCYP3A4NFKB1PMP22
SCHEMBL18470136 0.88 KMT2A (0.47) SCN2APOLBCYP3A4NFKB1PMP22
SCHEMBL4649466 0.84 POLB (0.65) POLBCYP3A4NFKB1PMP22GAA
SCHEMBL9324781 0.81 KMT2A (0.46) SCN2APOLBCYP3A4NFKB1PMP22
SCHEMBL18917454 0.80 CYP3A4 (0.65) SCN2APOLBCYP3A4NFKB1PMP22
SCHEMBL11860388 0.80 ADORA2A (0.62) SCN2APOLBCYP3A4NFKB1PMP22
SCHEMBL3382926 0.79 KMT2A (0.56) SCN2APOLBCYP3A4NFKB1PMP22
SCHEMBL3381865 0.79 KMT2A (0.56) SCN2APOLBCYP3A4NFKB1PMP22
SCHEMBL3380658 0.79 KMT2A (0.56) SCN2APOLBCYP3A4NFKB1PMP22
SCHEMBL18470140 0.79 KMT2A (0.46) SCN2APOLBCYP3A4NFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148043-B2 Silsesquioxane resin systems with base additives bearing electron-attracting functionalities DOW CORNING CORPORATION (US) 2012-04-03 US claimed
JP-2009543135-A 2009-12-03 JP claimed
US-20090202941-A1 SILSESQUIOXANE RESIN SYSTEMS WITH BASE ADDITIVES BEARING ELECTRON-ATTRACTING FUNCTIONALITIES DOW CORNING CORPORATION (US) 2009-08-13 US claimed
WO-2008002975-A2 SILSESQUIOXANE RESIN SYSTEMS WITH BASE ADDITIVES BEARING ELECTRON- ATTRACTING FUNCTIONALITIES DOW CORNING CORPORATION (US) 2008-01-03 WO claimed
US-20240337943-A1 HIGH REFRACTIVE INDEX PHOTORESIST COMPOSITION DOW SILICONES CORP (US) 2024-10-10 US disclosed
CN-118103773-A High refractive index photoresist composition 美国陶氏有机硅公司 2024-05-28 CN disclosed
US-20230321043-A1 COMPOUNDS HAVING PSEUDOMONAS ANTI-BIOFILM PROPERTIES UNIV COPENHAGEN (DK) 2023-10-12 US disclosed
US-20230321043-A1 COMPOUNDS HAVING PSEUDOMONAS ANTI-BIOFILM PROPERTIES UNIV COPENHAGEN (DK) 2023-10-12 US disclosed
WO-2023064023-A1 HIGH REFRACTIVE INDEX PHOTORESIST COMPOSITION DOW SILICONES CORPORATION (US) 2023-04-20 WO disclosed
US-11370888-B2 Silicon-rich silsesquioxane resins DOW SILICONES CORPORATION (US) 2022-06-28 US disclosed
CN-109415513-B Silicon-rich silsesquioxane resins 美国陶氏有机硅公司 2022-02-25 CN disclosed
US-20190211155-A1 SILICON-RICH SILSESQUIOXANE RESINS DOW SILICONES CORPORATION 2019-07-11 US disclosed
US-20010006767-A1 Developing solution and method of forming polyimide pattern by using the developing solution YOSHIAKI KAWAMONZEN 2001-07-05 US disclosed
US-6183934-B1 FOE USE IN FORMATION OF PATTERN OF INSULATION FILM, PASSIVATION FILM, .ALPHA.-RAY SHIELDING FILM, OPTICAL WAVEGUIDE KABUSHIKI KAISHA TOSHIBA (JP) 2001-02-06 US disclosed
US-6159654-A Negative photosensitive polymer composition of a thermosetting polymer precursor curable by cyclodehydration upon heating KABUSHIKI KAISHA TOSHIBA (JP) 2000-12-12 US disclosed
US-6001517-A A THERMOSETTING POLYMER WHICH CAN BE CURED THROUGH CYCLODEHYDRATION UPON HEATING AND A CURE ACCELERATOR WHICH CAN BE DEACTIVATED OF ITS CURE ACCELERATION PROPERTY BY IRRIDIATION OF LIGHT KABUSHIKI KAISHA TOSHIBA (JP) 1999-12-14 US disclosed
US-5578697-A DIELECTRIC POLYMERS FOR ELECTRONICS KABUSHIKI KAISHA TOSHIBA (JP) 1996-11-26 US disclosed
EP-0416749-B1 Substituted 4-aminoquinolines SMITHKLINE BEECHAM INTERCREDIT (NL) 1994-08-17 EP disclosed
US-5082841-A Enzyme inhibitor SMITHKLINE BEECHAM INTERCREDIT B.V. (GB) 1992-01-21 US disclosed
EP-0416749-A2 Substituted 4-aminoquinolines SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) 1991-03-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230321043-A1 COMPOUNDS HAVING PSEUDOMONAS ANTI-BIOFILM PROPERTIES GMPS, PDE11A, CGAS SCN2A 3326/4885POLB 320/4885CYP3A4 4726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.