Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ATP4A | P20648 | 1/20 | 0.38 |
| ▸ | ATP4B | P51164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL441950 | 0.99 | SMN1; SMN2 (0.39) | SMN1; SMN2ATP4AATP4BALDH1A1KMT2A | |
| SCHEMBL885589 | 0.89 | NPSR1 (0.40) | SMN1; SMN2ATP4AATP4BALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL436656 | 0.88 | NPSR1 (0.39) | SMN1; SMN2ATP4AATP4BALDH1A1KMT2A | |
| SCHEMBL2316431 | 0.79 | TP53 (0.46) | SMN1; SMN2ALDH1A1KMT2AMEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL438527 | 0.78 | TP53 (0.45) | SMN1; SMN2ALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL437304 | 0.76 | PTGS1 (0.39) | SMN1; SMN2ALDH1A1MAPK14LMNAHTT | |
| Hydrochloric Acid SCHEMBL436260 | 0.76 | PTGS1 (0.38) | SMN1; SMN2ALDH1A1MAPK14LMNAHTT | |
| SCHEMBL885515 | 0.68 | LRRK2 (0.48) | SMN1; SMN2ALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL5806352 | 0.67 | CYP1A2 (0.48) | SMN1; SMN2ALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL5808755 | 0.67 | CYP1A2 (0.48) | SMN1; SMN2ALDH1A1KMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784402-B1 | PYRROLO[3,2-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-08-03 | — | — | EP | claimed |
| EP-1784402-A1 | PYRROLO[3,2-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 2007-05-16 | — | — | EP | claimed |
| WO-2006025714-A1 | PYRROLO[3,2-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | claimed |
| EP-1784402-A1 | PYRROLO[3,2-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006025714-A1 | PYRROLO[3,2-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |