Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858885 | 1.00 | MAPT (0.64) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL8858878 | 1.00 | MAPT (0.64) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL8858868 | 1.00 | MAPT (0.64) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL8858890 | 1.00 | MAPT (0.64) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL8543514 | 0.85 | MAPKAPK2 (0.54) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8545321 | 0.85 | MAPKAPK2 (0.54) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3575730 | 0.85 | MAPKAPK2 (0.54) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8545315 | 0.85 | MAPKAPK2 (0.54) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8543519 | 0.85 | MAPKAPK2 (0.54) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31612407 | 0.79 | MEN1 (1.00) | MAPTLMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622957-A | INDUCERS OF TYROSINE HYDROXYLASE; TREATMENT OF DEPRESSION AND ANXIETY | ADIR ET COMPAGNIE (FR) | 1997-04-22 | — | — | US | disclosed |
| US-5602131-A | EburnanE analogues | ADIR ET COMPAGNIE (FR) | 1997-02-11 | — | — | US | disclosed |