SCHEMBL88594

SCHEMBL88594

c1cc2sccc2cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29788434 1.00
SCHEMBL17350114 0.98 CYP2A6 (0.40)
Potassium SCHEMBL17350115 0.98 CYP2A6 (0.40)
Lithium SCHEMBL11068561 0.98 CYP2A6 (0.40)
SCHEMBL11068559 0.98 CYP2A6 (0.40)
Hydrochloric Acid SCHEMBL3872997 0.98 CYP2A6 (0.40)
SCHEMBL27452809 0.98
Bromide SCHEMBL27975659 0.96 CYP2A6 (0.39)
Hydrochloric Acid SCHEMBL27379501 0.96 CYP2A6 (0.39)
Bromide SCHEMBL27975991 0.96 CYP2A6 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1937 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250075265-A1 ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS ROCHE SEQUENCING SOLUTIONS INC (US) 2025-03-06 US claimed
US-11970731-B2 Enhancement of nucleic acid polymerization by aromatic compounds Roche Sequencing Solutions, Inc. (US) 2024-04-30 US claimed
CN-116568675-A Cyclic isothiourea derivatives as CXCR4 modulators 埃尔米乌治疗公司 2023-08-08 CN claimed
EP-3735409-B1 ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS STRATOS GENOMICS INC (US) 2023-06-21 EP claimed
US-11547701-B2 Compounds and compositions for the inhibition of NAMPT VALO HEALTH, INC. (US) 2023-01-10 US claimed
EP-3994262-A1 ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS Stratos Genomics Inc. (US) 2022-05-11 EP claimed
US-20220112548-A1 ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS Roche Sequencing Solutions, Inc. 2022-04-14 US claimed
CN-114144520-A Enhanced nucleic acid polymerization by aromatic compounds 斯特拉托斯基因公司 2022-03-04 CN claimed
US-20210244717-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT Valo Health, LLC 2021-08-12 US claimed
US-20210062251-A1 ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS Roche Sequencing Solutions, Inc. 2021-03-04 US claimed
US-4886793-A PENICILLINS; HUMANS OR ANIMALS FARMITALIA CARLO ERBA, S.R.L. (IT) 1989-12-12 US claimed
EP-0236880-A2 Penem derivatives FARMITALIA CARLO ERBA S.r.l. (IT) 1987-09-16 EP claimed
EP-0099802-B1 THIENO(3,2-C) PYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR THERAPEUTICAL USE ELF SANOFI (FR) 1987-02-04 EP claimed
US-4501739-A BACTERICIDES, ANTIBIOTICS ELI LILLY AND COMPANY (US) 1985-02-26 US claimed
US-4480098-A Preparation of alkali metal thieno(furo)pyridines ELI LILLY AND COMPANY (US) 1984-10-30 US claimed
US-4406898-A ANTIBIOTICS CONTAINING A THIENOPYRIDINIUM OR FUROPYRIDINIUM GROUP ELI LILLY AND COMPANY (US) 1983-09-27 US claimed
EP-0031265-B1 PROCESS FOR THE CATALYTIC PREPARATION OF THIENO (3,2-C) PYRIDINE ELF SANOFI (FR) 1982-11-24 EP claimed
US-4311845-A Process for the preparation of thieno[3,2-c]pyridine SANOFI (FR) 1982-01-19 US claimed
US-4136186-A ANTICOAGULANTS, ANTIINFLAMMATORY AGENTS, SEDATIVES PARCOR (FR) 1979-01-23 US claimed
US-3969358-A Process for the preparation of thieno [3,2-c] pyridine and thieno [2,3-c] py PARCOR (FR) 1976-07-13 US claimed