Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | THPO | P40225 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8678601 | 1.00 | MAPK1 (0.50) | MAPK1HSD17B10KDM4ECYP3A4MAPT | |
| SCHEMBL8859491 | 0.83 | KDM4E (0.52) | MAPK1HSD17B10KDM4ECYP3A4MAPT | |
| SCHEMBL8677543 | 0.80 | APP (0.49) | MAPK1HSD17B10KDM4ECYP3A4MAPT | |
| SCHEMBL8859595 | 0.78 | KDM4E (0.55) | MAPK1HSD17B10KDM4ECYP3A4MAPT | |
| SCHEMBL8859593 | 0.76 | MAPT (0.56) | MAPK1HSD17B10KDM4ECYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL8676433 | 0.75 | NQO1 (0.48) | MAPK1HSD17B10KDM4ECYP3A4MAPT | |
| SCHEMBL29781217 | 0.75 | KDM4E (0.65) | MAPK1HSD17B10KDM4ECYP3A4MAPT | |
| SCHEMBL20254622 | 0.75 | KDM4E (0.65) | MAPK1HSD17B10KDM4ECYP3A4MAPT | |
| SCHEMBL20254520 | 0.75 | KDM4E (0.65) | MAPK1HSD17B10KDM4ECYP3A4MAPT | |
| SCHEMBL8677990 | 0.74 | KDM4E (0.51) | MAPK1HSD17B10KDM4ECYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720608-B1 | NOVEL DIHISPIDINE DERIVATIVES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-07-09 | — | — | EP | disclosed |