Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C8 | P10632 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL832720 | 0.93 | CYP2C8 (0.60) | CYP2C8KMT2APTGDR2MEN1ALDH1A1 | |
| SCHEMBL10255460 | 0.85 | CYP2C8 (0.44) | CYP2C8KMT2APTGDR2MEN1ALDH1A1 | |
| SCHEMBL12665812 | 0.78 | CYP2C8 (0.69) | CYP2C8KMT2APTGDR2MEN1ALDH1A1 | |
| SCHEMBL13906259 | 0.78 | CYP2C8 (0.79) | CYP2C8KMT2APTGDR2MEN1ALDH1A1 | |
| SCHEMBL832169 | 0.76 | CYP2C8 (0.61) | CYP2C8KMT2APTGDR2MEN1ALDH1A1 | |
| SCHEMBL13905161 | 0.76 | CYP2C8 (0.50) | CYP2C8KMT2APTGDR2MEN1ALDH1A1 | |
| SCHEMBL831122 | 0.75 | CYP2C8 (0.59) | CYP2C8KMT2APTGDR2MEN1ALDH1A1 | |
| SCHEMBL832443 | 0.74 | CYP2C8 (0.76) | CYP2C8KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL831903 | 0.73 | CYP2C8 (0.45) | CYP2C8KMT2APTGDR2MEN1ALDH1A1 | |
| SCHEMBL832115 | 0.73 | CYP2C8 (0.62) | CYP2C8KMT2APTGDR2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197842-B1 | 2, 3-SUBSTITUTED INDOLE DERIVATIVES FOR TREATING VIRAL INFECTIONS | SCHERING CORP (US) | 2012-05-23 | — | — | EP | disclosed |