Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10255265 | 0.85 | CYP2C8 (0.40) | CYP2C8KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL862423 | 0.84 | CYP2C8 (0.43) | CYP2C8KMT2A | |
| SCHEMBL832003 | 0.78 | CYP2C8 (0.48) | CYP2C8KMT2A | |
| SCHEMBL831983 | 0.77 | CYP2C8 (0.37) | CYP2C8KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL862447 | 0.76 | CYP2C8 (0.42) | CYP2C8KMT2A | |
| SCHEMBL831259 | 0.75 | CYP2C8 (0.39) | CYP2C8KMT2A | |
| SCHEMBL831989 | 0.75 | CYP2C8 (0.39) | CYP2C8KMT2ACYP2C9 | |
| SCHEMBL831116 | 0.75 | CYP2C8 (0.49) | CYP2C8KMT2A | |
| SCHEMBL862430 | 0.74 | CYP2C8 (0.45) | CYP2C8KMT2A | |
| SCHEMBL862437 | 0.74 | CYP2C8 (0.45) | CYP2C8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197842-B1 | 2, 3-SUBSTITUTED INDOLE DERIVATIVES FOR TREATING VIRAL INFECTIONS | SCHERING CORP (US) | 2012-05-23 | — | — | EP | disclosed |