Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL8862201

Cc1ccc([S+](c2ccc(C)cc2)c2ccc(OCC(=O)OC(C)(C)C)cc2)cc1.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSEN1 P49768 2/20 0.47
PSEN2 P49810 2/20 0.47
APH1B Q8WW43 2/20 0.47
NCSTN Q92542 2/20 0.47
APH1A Q96BI3 2/20 0.47
PSENEN Q9NZ42 2/20 0.47
PTPN1 P18031 1/20 0.41
GAA P10253 3/20 0.41
LMNA P02545 3/20 0.41
NPSR1 Q6W5P4 1/20 0.40
KCNH2 Q12809 1/20 0.40
L3MBTL1 Q9Y468 5/20 0.40
NPC1 O15118 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
MAPT P10636 3/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
RAB9A P51151 1/20 0.37
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL8862161 1.00 PSEN1 (0.47) PSEN1PSEN2APH1BNCSTNAPH1A
Trifluoromethanesulfonic Acid SCHEMBL8081855 0.95 PSEN1 (0.50) PSEN1PSEN2APH1BNCSTNAPH1A
Trifluoromethanesulfonic Acid SCHEMBL3197613 0.91 PTPN1 (0.48) PSEN1PSEN2APH1BNCSTNAPH1A
Trifluoromethanesulfonic Acid SCHEMBL8862183 0.91 PSEN1 (0.47) PSEN1PSEN2APH1BNCSTNAPH1A
Trifluoromethanesulfonic Acid SCHEMBL8862138 0.91 PTPN1 (0.48) PSEN1PSEN2APH1BNCSTNAPH1A
Trifluoromethanesulfonic Acid SCHEMBL8862208 0.91 PSEN1 (0.47) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL8862147 0.91 PSEN1 (0.46) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL8862192 0.91 PSEN1 (0.46) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL8069405 0.91 PSEN1 (0.46) PSEN1PSEN2APH1BNCSTNAPH1A
Trifluoromethanesulfonic Acid SCHEMBL8862165 0.89 PSEN1 (0.45) PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5679496-A CONTAINING SULFONIUM SALT HAVING TERT-BUTOXYCARBONYLMETHOXY GROUP(S) AS ACID LABILE GROUPS; SENSITIVITY, RESOLUTION, ETCH AND HEAT RESISTANCE SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-10-21 US disclosed