SCHEMBL8862467

SCHEMBL8862467

COc1cccc2c1OC1(C=C2)N(C)c2ccc(Cl)cc2C1(C)C.COc1cccc2c1OC1(C=C2)N(C)c2ccc(Cl)cc2C1(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.42
GAA P10253 4/20 0.42
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
LMNA P02545 3/20 0.42
RECQL P46063 3/20 0.42
TDP1 Q9NUW8 3/20 0.42
NPSR1 Q6W5P4 2/20 0.42
ALPG P10696 1/20 0.42
TP53 P04637 1/20 0.42
ALOX15 P16050 1/20 0.42
HSD17B10 Q99714 1/20 0.42
GFER P55789 1/20 0.39
THRB P10828 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
PLIN1 O60240 1/20 0.35
PKM P14618 1/20 0.35
TSHR P16473 1/20 0.35
PLIN5 Q00G26 1/20 0.35
ABHD5 Q8WTS1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8680467 1.00 MAPT (0.42) MAPTGAAMEN1KMT2ALMNA
SCHEMBL8863252 0.89 MAPT (0.43) MAPTGAAMEN1KMT2ALMNA
SCHEMBL8680550 0.89 GAA (0.40) MAPTGAAMEN1KMT2ALMNA
SCHEMBL8680344 0.88 MAPT (0.44) MAPTGAAMEN1KMT2ALMNA
SCHEMBL8685210 0.88 MAPT (0.40) MAPTGAAMEN1KMT2ALMNA
SCHEMBL8682315 0.87 MAPT (0.42) MAPTGAAMEN1KMT2ALMNA
SCHEMBL6102948 0.85 MAPT (0.54) MAPTGAAMEN1KMT2ALMNA
SCHEMBL29532854 0.85 MAPT (0.54) MAPTGAAMEN1KMT2ALMNA
SCHEMBL8685206 0.85 MAPT (0.43) MAPTGAAMEN1KMT2ALMNA
SCHEMBL8680694 0.85 GAA (0.39) MAPTGAAMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5633109-A Ink compositions with liposomes containing photochromic compounds XEROX CORPORATION (US) 1997-05-27 US disclosed