SCHEMBL8862845

SCHEMBL8862845

CC1=N[C@H](c2ccccc2)CO1

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 7/20 0.61
MAPT P10636 2/20 0.51
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
ALDH1A1 P00352 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6630553 1.00 TAAR1 (0.61) TAAR1MAPTNPC1RAB9AALDH1A1
SCHEMBL20289497 1.00 TAAR1 (0.61) TAAR1MAPTNPC1RAB9AALDH1A1
SCHEMBL7554386 0.86 TAAR1 (0.50) TAAR1MAPTNPC1RAB9AALDH1A1
SCHEMBL20385724 0.81 TAAR1 (0.64) TAAR1
SCHEMBL20385752 0.81 TAAR1 (0.42) TAAR1ALDH1A1
SCHEMBL20385801 0.81 TAAR1 (0.42) TAAR1ALDH1A1
SCHEMBL1315541 0.79 TAAR1 (0.56) TAAR1MAPTNPC1RAB9AALDH1A1
SCHEMBL485591 0.79 TAAR1 (0.56) TAAR1MAPTNPC1RAB9AALDH1A1
SCHEMBL485589 0.79 TAAR1 (0.56) TAAR1MAPTNPC1RAB9AALDH1A1
SCHEMBL19367694 0.79 MAPT (0.67) TAAR1MAPTNPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116354802-A Preparation method of chiral benzyl secondary alcohol compound 上海毕得医药科技股份有限公司 2023-06-30 CN claimed
JP-9087258-A None JP disclosed
CN-116354802-A Preparation method of chiral benzyl secondary alcohol compound 上海毕得医药科技股份有限公司 2023-06-30 CN disclosed
JP-H0987258-A OXAZOLINES, THEIR PRODUCTION AND PRODUCTION OF ASYMMETRIC CYCLOPROPANECARBOXYLIC ACIDS SUMITOMO CHEM CO LTD 1997-03-31 JP disclosed