⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8863188 | 1.00 | — | — | |
| SCHEMBL38426 | 0.90 | NPC1 (0.33) | — | |
| SCHEMBL38425 | 0.90 | NPC1 (0.33) | — | |
| SCHEMBL10973466 | 0.89 | EPHX1 (0.35) | — | |
| SCHEMBL10973436 | 0.89 | EPHX1 (0.35) | — | |
| SCHEMBL2773414 | 0.87 | NPC1 (0.36) | — | |
| SCHEMBL2773413 | 0.87 | NPC1 (0.36) | — | |
| SCHEMBL17611111 | 0.84 | — | — | |
| SCHEMBL17611112 | 0.84 | — | — | |
| SCHEMBL8922946 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2270003-A1 | Novel processes for the preparation of a 2H-chromene | Acino Pharma AG (CH) | 2011-01-05 | — | — | EP | disclosed |
| US-20080221324-A1 | Novel Processes For The Preparation Of A 2H-Chromene | ARPIDA (CH) | 2008-09-11 | — | — | US | disclosed |
| US-20080221324-A1 | Novel Processes For The Preparation Of A 2H-Chromene | ARPIDA (CH) | 2008-09-11 | — | — | US | disclosed |
| US-5618949-A | Process for synthesis of chiral cis- and trans-3-amino-4-substituted pyrrolidine compounds | ABBOTT LABORATORIES (US) | 1997-04-08 | — | — | US | disclosed |
| US-4419356-A | 2,3,6,7-Tetrahydrothiazolo[3,2-a]pyrimidine derivatives having anti-rheumatic properties and pharmaceutical compositions containing them | RHONE-POULENC INDUSTRIES (FR) | 1983-12-06 | — | — | US | disclosed |
| US-4000315-A | Cyclopropane esters for the control of mites | ZOECON CORPORATION (US) | 1976-12-28 | — | — | US | disclosed |
| US-3957849-A | MITICIDES | ZOECON CORPORATION (US) | 1976-05-18 | — | — | US | disclosed |