Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764712 | 1.00 | STAT3 (0.46) | STAT3L3MBTL1TSHRTBXAS1LTB4R | |
| SCHEMBL10449020 | 1.00 | STAT3 (0.46) | STAT3L3MBTL1TSHRTBXAS1LTB4R | |
| SCHEMBL30850377 | 1.00 | STAT3 (0.46) | STAT3L3MBTL1TSHRTBXAS1LTB4R | |
| SCHEMBL8864017 | 1.00 | STAT3 (0.46) | STAT3L3MBTL1TSHRTBXAS1LTB4R | |
| SCHEMBL17614843 | 1.00 | STAT3 (0.46) | STAT3L3MBTL1TSHRTBXAS1LTB4R | |
| SCHEMBL9458218 | 1.00 | STAT3 (0.46) | STAT3L3MBTL1TSHRTBXAS1LTB4R | |
| SCHEMBL25030574 | 1.00 | STAT3 (0.46) | STAT3L3MBTL1TSHRTBXAS1LTB4R | |
| SCHEMBL7827739 | 1.00 | STAT3 (0.46) | STAT3L3MBTL1TSHRTBXAS1LTB4R | |
| SCHEMBL6238329 | 0.98 | STAT3 (0.47) | STAT3L3MBTL1TSHRTBXAS1LTB4R | |
| SCHEMBL17951934 | 0.96 | TBXA2R (0.43) | STAT3L3MBTL1TSHRTBXAS1LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525479-B1 | Spicamycin derivatives and the use thereof | KIRIN BREWERY (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5631238-A | ANTICARCINOGENIC AGENTS | KIRIN BEER KABUSHIKI KAISHA (JP) | 1997-05-20 | — | — | US | disclosed |
| US-5461036-A | Treating colon, gastric, esophageal cancer | KIRIN BEER KABUSHIKI KAISHA (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0525479-A1 | Spicamycin derivatives and the use thereof | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-02-03 | — | — | EP | disclosed |