Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | PLG | P00747 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 6/20 | 0.55 |
| ▸ | PPARD | Q03181 | 6/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3408123 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL6575728 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL10004661 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL4609065 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL8864071 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL7221658 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL1706463 | 1.00 | — | — | |
| SCHEMBL434540 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL9096720 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL28985038 | 1.00 | TSHR (0.71) | TSHRLMNANFKB1PMP22ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525479-B1 | Spicamycin derivatives and the use thereof | KIRIN BREWERY (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5631238-A | ANTICARCINOGENIC AGENTS | KIRIN BEER KABUSHIKI KAISHA (JP) | 1997-05-20 | — | — | US | disclosed |
| US-5461036-A | Treating colon, gastric, esophageal cancer | KIRIN BEER KABUSHIKI KAISHA (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0525479-A1 | Spicamycin derivatives and the use thereof | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-02-03 | — | — | EP | disclosed |