Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8863672 | 0.86 | TSHR (0.36) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL4596155 | 0.85 | TSHR (0.42) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL544590 | 0.84 | TSHR (0.45) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL153584 | 0.79 | TSHR (0.41) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL8961961 | 0.79 | TSHR (0.41) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL28092410 | 0.78 | TSHR (0.34) | TSHRHPGD | |
| SCHEMBL8962107 | 0.77 | TSHR (0.44) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL8863644 | 0.77 | TSHR (0.41) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL1507509 | 0.77 | TSHR (0.40) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL27813096 | 0.77 | TSHR (0.40) | TSHRHPGDTHRBALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658988-A | ONE-PACKAGE; AUTOMOBILE FINISHES | KANSAI PAINT CO., LTD. (JP) | 1997-08-19 | — | — | US | disclosed |