Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.35 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.31 |
| ▸ | SCN2B | O60939 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.31 |
| ▸ | KRAS | P01116 | 4/20 | 0.31 |
| ▸ | SCN4A | P35499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL831480 | 0.94 | CYP2C8 (0.39) | CYP2C8AURKATPX2TRPM4SCN9A | |
| SCHEMBL13905361 | 0.92 | CYP2C8 (0.38) | CYP2C8AURKATPX2SCN9AKMT2A | |
| SCHEMBL10257265 | 0.90 | CYP2C8 (0.41) | CYP2C8AURKATPX2TRPM4SCN9A | |
| SCHEMBL831406 | 0.89 | CYP2C8 (0.43) | CYP2C8AURKATPX2TRPM4SCN9A | |
| SCHEMBL13905195 | 0.88 | CYP2C8 (0.38) | CYP2C8AURKATPX2TRPM4SCN9A | |
| SCHEMBL831037 | 0.86 | CYP2C8 (0.42) | CYP2C8AURKATPX2TRPM4SCN9A | |
| SCHEMBL831390 | 0.86 | CYP2C8 (0.39) | CYP2C8AURKATPX2SCN9AKMT2A | |
| SCHEMBL831763 | 0.85 | CYP2C8 (0.40) | CYP2C8AURKATPX2TRPM4SCN9A | |
| SCHEMBL832072 | 0.85 | CYP2C8 (0.36) | CYP2C8AURKATPX2SCN9AKMT2A | |
| SCHEMBL831906 | 0.85 | SCN9A (0.38) | CYP2C8SCN9AKMT2ASCN5ASCN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197842-B1 | 2, 3-SUBSTITUTED INDOLE DERIVATIVES FOR TREATING VIRAL INFECTIONS | SCHERING CORP (US) | 2012-05-23 | — | — | EP | disclosed |
| WO-2009032116-A1 | 2, 3-SUBSTITUTED INDOLE DERIVATIVES FOR TREATING VIRAL INFECTIONS | SCHERING CORPORATION (US) | 2009-03-12 | — | — | WO | disclosed |