Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | CASP1 | P29466 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430419 | 0.84 | POLB (0.44) | HSD17B10KMT2AMAPTHTTGAA | |
| Hydrochloric Acid SCHEMBL1131404 | 0.83 | POLB (0.43) | HSD17B10KMT2AMAPTHTTGAA | |
| SCHEMBL10941837 | 0.77 | KDM4E (0.49) | HSD17B10KMT2AMAPTHTTGAA | |
| SCHEMBL10624847 | 0.77 | KDM4E (0.52) | HSD17B10KMT2AMAPTHTTGAA | |
| SCHEMBL9596191 | 0.76 | HTT (0.47) | HSD17B10MAPTHTTGAATP53 | |
| SCHEMBL2910532 | 0.76 | POLB (0.62) | HSD17B10KMT2AMAPTHTTGAA | |
| SCHEMBL9121576 | 0.75 | HTT (0.39) | HSD17B10KMT2AMAPTHTTGAA | |
| SCHEMBL11183137 | 0.75 | KMT2A (0.48) | HSD17B10KMT2AMAPTHTTGAA | |
| SCHEMBL721909 | 0.74 | HTT (0.59) | HSD17B10MAPTHTTGAATP53 | |
| SCHEMBL8714027 | 0.74 | GAA (0.47) | HSD17B10KMT2AMAPTHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674876-A | ANTIPROLIFERATIVE,-CARCINOGENIC AND -TUMOR AGENTS; SKIN DISORDERS; FREE RADICAL SCAVENGERS | RESEARCH DEVELOPMENT FOUNDATION (US) | 1997-10-07 | — | — | US | disclosed |
| WO-1996022089-A1 | p-HETEROATOM-SUBSTITUTED PHENOLS AND USES THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 1996-07-25 | — | — | WO | disclosed |