Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 5/20 | 0.46 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | CYCS | P99999 | 4/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865339 | 0.87 | SYK (0.40) | PDE3BPDE3AP2RY12SYKDGAT2 | |
| SCHEMBL8908003 | 0.82 | FFAR1 (0.51) | TOP1CYCSFFAR1 | |
| SCHEMBL8907994 | 0.81 | TOP1 (0.45) | ABCG2TOP1CYCSFFAR1 | |
| Hydrochloric Acid SCHEMBL8865123 | 0.81 | TOP1 (0.44) | ABCG2TOP1CYCSFFAR1 | |
| SCHEMBL16247124 | 0.79 | TOP1 (0.45) | ABCG2ALDH1A1TOP1CYCS | |
| SCHEMBL8907738 | 0.79 | ABCG2 (0.49) | SYKDGAT2ABCG2TOP1CYCS | |
| SCHEMBL21476713 | 0.78 | FFAR1 (0.64) | SYKCYP4F2CYP4A11FFAR1 | |
| SCHEMBL19718117 | 0.77 | CYSLTR2 (0.47) | PDE3BPDE3AP2RY12 | |
| SCHEMBL8903063 | 0.75 | TDP1 (0.56) | SYKCYP4F2CYP4A11FFAR1 | |
| SCHEMBL8909228 | 0.75 | GRIN2D (0.53) | MAPTABCG2KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684948-B1 | MESO-TETRAPHENYL PORPHYRIN COMPLEX COMPOUNDS, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICALS CONTAINING THE SAME | DIAGNOSTIKFORSCHUNG INST (DE) | 1997-10-22 | — | — | EP | disclosed |
| US-5674467-A | USED IN NMR DIAGNOSIS, RADIODIAGNOSIS OR RADIOTHERAPY | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 1997-10-07 | — | — | US | disclosed |
| WO-1994019352-A1 | MESO-TETRAPHENYL PORPHYRIN COMPLEX COMPOUNDS, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICALS CONTAINING THE SAME | Institut für Diagnostikforschung GmbH an der Freien Universität Berlin (DE) | 1994-09-01 | — | — | WO | disclosed |