Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 4/20 | 0.60 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1994985 | 0.84 | GFER (0.68) | GFERMAOBMAOARECQLALDH1A1 | |
| SCHEMBL2914010 | 0.84 | GFER (0.77) | GFERMAOBMAOARECQLALDH1A1 | |
| SCHEMBL12110702 | 0.84 | GFER (0.77) | GFERMAOBMAOARECQLALDH1A1 | |
| SCHEMBL3111509 | 0.84 | MAOB (0.80) | GFERMAOBMAOARECQLALDH1A1 | |
| SCHEMBL421341 | 0.84 | GFER (0.77) | GFERMAOBMAOARECQLALDH1A1 | |
| SCHEMBL4021564 | 0.81 | MAOB (0.76) | GFERMAOBMAOARECQLALDH1A1 | |
| SCHEMBL4020067 | 0.81 | MAOB (0.76) | GFERMAOBMAOARECQLALDH1A1 | |
| SCHEMBL12110816 | 0.81 | MAOB (0.76) | GFERMAOBMAOARECQLALDH1A1 | |
| SCHEMBL4022346 | 0.81 | MAOB (0.76) | GFERMAOBMAOARECQLALDH1A1 | |
| SCHEMBL20251158 | 0.81 | MAOB (0.76) | GFERMAOBMAOARECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |
| US-4332809-A | ANTIALLERGENS | TANABE SEIYAKU CO., LTD. (JP) | 1982-06-01 | — | — | US | disclosed |