Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867344 | 0.90 | HPGD (0.61) | HPGDLMNAHTTSMN1; SMN2ADRB2 | |
| SCHEMBL8867037 | 0.88 | HPGD (0.67) | HPGDLMNAHTTSMN1; SMN2CA12 | |
| SCHEMBL8866945 | 0.85 | HPGD (0.53) | HPGDLMNAHTTSMN1; SMN2ADRB2 | |
| SCHEMBL7761720 | 0.82 | HPGD (0.58) | HPGDLMNAHTTSMN1; SMN2CA12 | |
| SCHEMBL7761718 | 0.79 | HPGD (0.55) | HPGDLMNAHTTSMN1; SMN2ADRB2 | |
| SCHEMBL7847086 | 0.79 | HPGD (0.66) | HPGDLMNAHTTSMN1; SMN2CA12 | |
| SCHEMBL5452372 | 0.79 | GAA (0.51) | HPGDLMNAHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL9592749 | 0.77 | HPGD (0.63) | HPGDLMNAHTTSMN1; SMN2CA12 | |
| SCHEMBL20245278 | 0.77 | HPGD (0.71) | HPGDLMNAHTTSMN1; SMN2CA2 | |
| SCHEMBL10191923 | 0.77 | CA1 (0.53) | HPGDLMNAHTTSMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |