Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | NAMPT | P43490 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | CCR5 | P51681 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866886 | 0.93 | KMT2A (0.68) | KMT2AMEN1LMNAGLANAMPT | |
| SCHEMBL8867200 | 0.92 | PTPN1 (0.66) | KMT2AMEN1LMNAGLAMAPT | |
| SCHEMBL8867807 | 0.86 | KMT2A (0.72) | KMT2AMEN1LMNAGLANAMPT | |
| SCHEMBL14349959 | 0.85 | KMT2A (0.70) | KMT2AMEN1LMNAGLANAMPT | |
| SCHEMBL29565532 | 0.82 | KMT2A (0.66) | KMT2AMEN1LMNAGLANAMPT | |
| SCHEMBL30182449 | 0.81 | KMT2A (0.74) | KMT2AMEN1LMNAGLANAMPT | |
| SCHEMBL30182461 | 0.81 | KMT2A (0.74) | KMT2AMEN1LMNAGLANAMPT | |
| SCHEMBL9610938 | 0.81 | KMT2A (0.74) | KMT2AMEN1LMNAGLANAMPT | |
| SCHEMBL2579208 | 0.81 | KMT2A (0.74) | KMT2AMEN1LMNAGLANAMPT | |
| SCHEMBL2790788 | 0.80 | KMT2A (0.68) | KMT2AMEN1LMNAGLANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |