Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.60 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.60 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.60 |
| ▸ | ALB | P02768 | 1/20 | 0.60 |
| ▸ | PGR | P06401 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.59 |
| ▸ | APEX1 | P27695 | 3/20 | 0.59 |
| ▸ | APAF1 | O14727 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.59 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.59 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.59 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868312 | 1.00 | NR1I2 (0.62) | NR1I2HTR2CKMT2APPARGMAPT | |
| SCHEMBL10644623 | 0.91 | TDP1 (0.60) | NR1I2HTR2CKMT2APPARGMAPT | |
| SCHEMBL10643291 | 0.91 | TDP1 (0.60) | NR1I2HTR2CKMT2APPARGMAPT | |
| SCHEMBL8868976 | 0.91 | PTGS1 (0.53) | NR1I2HTR2CKMT2APPARGMAPT | |
| SCHEMBL8868981 | 0.91 | PTGS1 (0.53) | NR1I2HTR2CKMT2APPARGMAPT | |
| SCHEMBL8869412 | 0.90 | KMT2A (0.50) | NR1I2HTR2CKMT2APPARGMAPT | |
| SCHEMBL8869406 | 0.90 | KMT2A (0.50) | NR1I2HTR2CKMT2APPARGMAPT | |
| SCHEMBL10875895 | 0.89 | TDP1 (0.62) | NR1I2HTR2CKMT2APPARGMAPT | |
| SCHEMBL8867830 | 0.89 | TDP1 (0.73) | NR1I2HTR2CKMT2APPARGMAPT | |
| SCHEMBL11391493 | 0.89 | TDP1 (0.73) | NR1I2HTR2CKMT2APPARGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594132-A | ANTIBIOTIC | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| US-5026695-A | Gram negative-gram positive microbiocides, oral adminis tration | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-06-25 | — | — | US | disclosed |
| US-4904652-A | 7-acylamino-3-substituted cephalosporanic acid derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-27 | — | — | US | disclosed |
| US-4462999-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-31 | — | — | US | disclosed |
| US-4409215-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-10-11 | — | — | US | disclosed |
| EP-0029557-A2 | 7-Acylamino-3-substituted cephalosporanic acid derivatives, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-06-03 | — | — | EP | disclosed |