Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | ABCC4 | O15439 | 3/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.56 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.56 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.56 |
| ▸ | ALB | P02768 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 3/20 | 0.53 |
| ▸ | APAF1 | O14727 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.53 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.53 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868929 | 1.00 | TDP1 (0.60) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL7645328 | 0.86 | TDP1 (0.68) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL7645326 | 0.86 | TDP1 (0.68) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL11034342 | 0.84 | TDP1 (0.70) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL11034346 | 0.84 | TDP1 (0.70) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL6888259 | 0.84 | TDP1 (0.67) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL6888250 | 0.84 | TDP1 (0.67) | TDP1MAPTABCC4CNR1CTDSP1 | |
| Trifluoroacetic Acid SCHEMBL9145278 | 0.83 | NR1I2 (0.60) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL7645129 | 0.82 | TDP1 (0.65) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL7645134 | 0.82 | TDP1 (0.65) | TDP1MAPTABCC4CNR1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607926-A | ACTIVE AGAINST METHICILLIN RESISTANT BACTERIA | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-03-04 | — | — | US | disclosed |
| US-5604218-A | EXHIBITS ACTIVITY AGAINST METHICILLIN RESISTANT BACTERIA | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-02-18 | — | — | US | disclosed |
| US-5593986-A | Cephalosporin antibiotics | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-01-14 | — | — | US | disclosed |