Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868676 | 1.00 | MAPT (0.49) | MAPTMEN1KMT2ABCL2L1MCL1 | |
| SCHEMBL8869489 | 0.92 | PPARA (0.50) | MAPTMEN1KMT2ABCL2L1MCL1 | |
| SCHEMBL8868754 | 0.92 | PPARA (0.48) | MAPTMEN1KMT2AP4HTMPPARA | |
| SCHEMBL8869237 | 0.92 | PPARA (0.50) | MAPTMEN1KMT2ABCL2L1MCL1 | |
| SCHEMBL8868842 | 0.92 | P4HTM (0.48) | MAPTMEN1KMT2AP4HTMPPARA | |
| SCHEMBL8868685 | 0.91 | MAPT (0.52) | MAPTMEN1KMT2ABCL2L1MCL1 | |
| SCHEMBL8868460 | 0.91 | MAPT (0.52) | MAPTMEN1KMT2ABCL2L1MCL1 | |
| SCHEMBL9140344 | 0.91 | MAPT (0.53) | MAPTMEN1KMT2ABCL2L1MCL1 | |
| SCHEMBL9140652 | 0.91 | MAPT (0.53) | MAPTMEN1KMT2ABCL2L1MCL1 | |
| SCHEMBL8869223 | 0.91 | P4HTM (0.55) | MAPTMEN1KMT2AP4HTMPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |