Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869014 | 0.94 | P4HTM (0.54) | P4HTMRAB9ANPC1SMN1; SMN2HIF1A | |
| SCHEMBL8868570 | 0.93 | HIF1A (0.48) | P4HTMRAB9ANPC1SMN1; SMN2HIF1A | |
| SCHEMBL8868993 | 0.93 | NPC1 (0.47) | P4HTMRAB9ANPC1SMN1; SMN2HIF1A | |
| SCHEMBL9137550 | 0.92 | P4HTM (0.65) | P4HTMRAB9ANPC1SMN1; SMN2HIF1A | |
| SCHEMBL8868901 | 0.92 | P4HTM (0.51) | P4HTMRAB9ANPC1SMN1; SMN2HIF1A | |
| SCHEMBL8869157 | 0.91 | P4HTM (0.50) | P4HTMRAB9ANPC1SMN1; SMN2HIF1A | |
| SCHEMBL8868628 | 0.91 | P4HTM (0.50) | P4HTMRAB9ANPC1SMN1; SMN2HIF1A | |
| SCHEMBL8870254 | 0.90 | P4HTM (0.48) | P4HTMRAB9ANPC1SMN1; SMN2HIF1A | |
| SCHEMBL8869159 | 0.90 | P4HTM (0.58) | P4HTMRAB9ANPC1SMN1; SMN2HIF1A | |
| SCHEMBL8869628 | 0.89 | CA1 (0.54) | P4HTMRAB9ANPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |