Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL624843 | 1.00 | TSHR (0.46) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL3690718 | 1.00 | TSHR (0.46) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL183421 | 1.00 | TSHR (0.46) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL2932240 | 0.98 | TSHR (0.42) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL5078159 | 0.94 | TSHR (0.41) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL8111294 | 0.94 | TSHR (0.41) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL2136218 | 0.91 | TSHR (0.42) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL4052642 | 0.88 | TSHR (0.52) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL10701544 | 0.86 | MAPT (0.39) | TSHRMAPTABCC4ALDH1A1LMNA | |
| SCHEMBL7296275 | 0.85 | TSHR (0.41) | TSHRMAPTABCC4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859083-B1 | FIBERS MADE FROM COPOLYMERS OF ETHYLENE/ALPHA-OLEFINS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-01-18 | — | — | EP | disclosed |
| EP-1506259-A1 | EXTRUDABLE THERMOPLASTIC COMPOSITIONS | 3M Innovative Properties Company (US) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003099935-A1 | EXTRUDABLE THERMOPLASTIC COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-04 | — | — | WO | disclosed |
| US-6444736-B1 | MIXTURE; USING COORDINATION CATALYST | CHISSO CORPORATION (JP) | 2002-09-03 | — | — | US | disclosed |
| EP-0112568-B1 | GLASS-REINFORCED POLYMER COMPOSITION | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1986-11-05 | — | — | EP | disclosed |