Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869085 | 0.96 | P4HTM (0.52) | P4HTMRAB9AALDH1A1HPGDFBP1 | |
| SCHEMBL8870268 | 0.95 | P4HTM (0.47) | P4HTMRAB9AALDH1A1HPGDFBP1 | |
| SCHEMBL8868132 | 0.94 | SMN1; SMN2 (0.47) | P4HTMRAB9AHPGDFBP1MAPT | |
| SCHEMBL8869595 | 0.93 | P4HTM (0.49) | P4HTMRAB9AALDH1A1HPGDMAPT | |
| SCHEMBL8869621 | 0.93 | P4HTM (0.45) | P4HTMRAB9AHPGDFBP1MAPT | |
| SCHEMBL9139573 | 0.92 | P4HTM (0.48) | P4HTMRAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL8869015 | 0.92 | P4HTM (0.48) | P4HTMRAB9AALDH1A1HPGDMAPT | |
| SCHEMBL9141444 | 0.92 | P4HTM (0.59) | P4HTMRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL8870894 | 0.91 | P4HTM (0.48) | P4HTMRAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL8868688 | 0.91 | P4HTM (0.47) | P4HTMRAB9AALDH1A1HPGDFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |