Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869243 | 0.97 | P4HTM (0.47) | P4HTMNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8868669 | 0.95 | P4HTM (0.49) | P4HTMNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8869197 | 0.93 | NPC1 (0.46) | P4HTMNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8867891 | 0.92 | P4HTM (0.48) | P4HTMNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8868326 | 0.92 | P4HTM (0.50) | P4HTMNPC1RAB9ASMN1; SMN2MLYCD | |
| SCHEMBL8867435 | 0.91 | NPC1 (0.46) | P4HTMNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8869875 | 0.90 | P4HTM (0.48) | P4HTMNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8870171 | 0.90 | P4HTM (0.49) | P4HTMNPC1RAB9ASMN1; SMN2MLYCD | |
| SCHEMBL8869654 | 0.90 | P4HTM (0.51) | P4HTMEPHX2CA2 | |
| SCHEMBL9141434 | 0.90 | P4HTM (0.51) | P4HTMNPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |