Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867950 | 0.94 | P4HTM (0.48) | P4HTMKMT2AMEN1PPARARAB9A | |
| SCHEMBL8869506 | 0.94 | P4HTM (0.50) | P4HTMKMT2AMEN1PPARARAB9A | |
| SCHEMBL8869509 | 0.93 | SMN1; SMN2 (0.54) | P4HTMKMT2AMEN1ALDH1A1PPARA | |
| SCHEMBL8867921 | 0.91 | MAPT (0.54) | P4HTMKMT2AMEN1ALDH1A1PPARA | |
| SCHEMBL8869589 | 0.91 | MAPT (0.54) | P4HTMKMT2AMEN1ALDH1A1PPARA | |
| SCHEMBL8868823 | 0.91 | SMN1; SMN2 (0.50) | P4HTMKMT2AMEN1ALDH1A1PPARA | |
| SCHEMBL8868573 | 0.91 | BCL2L1 (0.51) | P4HTMKMT2AMEN1PPARARAB9A | |
| SCHEMBL8867935 | 0.91 | BCL2L1 (0.51) | P4HTMKMT2AMEN1PPARARAB9A | |
| SCHEMBL8869027 | 0.90 | P4HTM (0.55) | P4HTMKMT2AMEN1ALDH1A1PPARA | |
| SCHEMBL9139317 | 0.90 | P4HTM (0.55) | P4HTMKMT2AMEN1ALDH1A1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |