Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 4/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5549677 | 1.00 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HSD17B10PREP | |
| SCHEMBL5549676 | 1.00 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HSD17B10PREP | |
| SCHEMBL15635071 | 0.87 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HSD17B10PREP | |
| SCHEMBL14724992 | 0.87 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HSD17B10PREP | |
| SCHEMBL12295954 | 0.87 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HSD17B10PREP | |
| SCHEMBL14714350 | 0.87 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HSD17B10PREP | |
| SCHEMBL19838965 | 0.86 | CHRM2 (0.53) | CHRM2CHRM1CHRM3HSD17B10PREP | |
| SCHEMBL5832813 | 0.86 | CHRM2 (0.44) | CHRM2CHRM1CHRM3HSD17B10PREP | |
| SCHEMBL8205840 | 0.86 | CHRM2 (0.44) | CHRM2CHRM1CHRM3HSD17B10PREP | |
| SCHEMBL12328185 | 0.86 | CHRM2 (0.44) | CHRM2CHRM1CHRM3HSD17B10PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |